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This clinical case report illustrates an example of chronic myeloid leukaemia (CML). The XN-Series analyser identified abnormal scattergrams and multiple flags such as ‘Blasts/Abn Lympho?’, ‘IG Present’ or ‘Basophilia’. These findings led to a blood smear and digital imaging identified massive numbers of neutrophils and IG.
The lab information card explains how the MWO (monocytosis workflow optimisation) optimises the workflow and improves CMML detection in samples with monocytosis by using the ‘monodysplasia score’, monocyte count and information from the WBC scattergram.
The lab information card illustrates the value of the RET channel and points to the advanced clinical parameter RET-He (reticulocyte haemoglobin equivalent) and IRF (immature reticulocyte fraction). Front side addresses the core message for lab and clinical benefits, flip side contains technical information
This white paper intents to give an overview of the most common types of anaemia with a focus on how haematological parameters such as RET-He and other advanced RBC parameters help to distinguish different causes of anaemia. The white paper also summarises current guidelines and publications on advanced RBC parameters in order to help clinicians in choosing the appropriate treatment for the individual patient.
Haemostasis is a complex process that helps to keep the blood in a fluid state and prevent blood loss at the site of injury. While the intact endothelium of blood vessels has an anti-thrombogenic function that prevents blood coagulation, in the case of vessel wall damage, the exposed sub-endothelial components initiate the formation of a clot that will stop blood loss.