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This article describes a comprehensive reference interval study for the Sysmex XE-5000 haematological analyser, covering all diagnostic and many research parameters. A special feature is frequency distribution curves for all examined parameters which provide useful insight on the type of distribution for each test.
The Blood Bank mode (BB mode) is an optional mode for blood product measurement and quantification of residual cells left in the manufactured blood products. The front side of the lab information card gives an overview of blood component analysis and explains the benefit of the BB mode. The flip side presents information about sample types, technological requirements, workflow enhancements and specifications of the mode.
Aneuploidy is defined as the addition or deletion of chromosomes compared to the ‘normal’ number of chromosomes as a multiple of the haploid chromosome number. Aneuploidy is probably the most common type of chromosomal aberration in the plant kingdom.
Platelets are normally measured by impedance, but when interferences are present, this may lead to a wrong count. There are alternatives methods for platelet measurement that are here explained in detailed, like the fluorescence flow cytometry and the accurate count provided by the PLT-F channel.
In patients treated with haemodialysis (HD), the interaction with the dialysis membrane can disturb haemostatic balance. Interaction of platelets with the membrane can lead to platelet activation and adhesion, which both affects membrane performance and the viability of platelets. By looking at platelet characteristics and morphology, as well as markers of platelet activation, this process can be characterized in more detail.
Pathology laboratories can improve the quality of the analytical results, turnaround time and patient management. The awareness of the pre-analytical variables and their effects on haematology testing is the first step in ensuring that results can become consistently accurate.
Every step in the process of phlebotomy affects the quality of the specimen and is thus important for preventing laboratory error and patient injury. This document provides guidance on blood sampling and reiterates the accepted principles for drawing and collecting blood.