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Platelets are normally measured by impedance, but when interferences are present, this may lead to a wrong count. There are alternatives methods for platelet measurement that are here explained in detailed, like the fluorescence flow cytometry and the accurate count provided by the PLT-F channel.
In patients treated with haemodialysis (HD), the interaction with the dialysis membrane can disturb haemostatic balance. Interaction of platelets with the membrane can lead to platelet activation and adhesion, which both affects membrane performance and the viability of platelets. By looking at platelet characteristics and morphology, as well as markers of platelet activation, this process can be characterized in more detail.
Pathology laboratories can improve the quality of the analytical results, turnaround time and patient management. The awareness of the pre-analytical variables and their effects on haematology testing is the first step in ensuring that results can become consistently accurate.
Every step in the process of phlebotomy affects the quality of the specimen and is thus important for preventing laboratory error and patient injury. This document provides guidance on blood sampling and reiterates the accepted principles for drawing and collecting blood.