The Sysmex haemostasis reagent portfolio offers a broad range of well-established reagents, supporting laboratories with reliable, efficient and standardised testing solutions across routine and specialised haemostasis applications.

From PT, APTT and fibrinogen testing to factor assays, anticoagulant therapy monitoring and HISCL immunoassays, our reagents support accurate clinical decision-making throughout the patient pathway.

Built on the Four Powers – Trust, Mastery, Synergy and Growth – this approach brings together the essential strengths required for consistent performance in modern haemostasis diagnostics.

Consistency and innovation in every test

Comprehensive portfolio of routine and specialised haemostasis reagents for PT, APTT, fibrinogen, D-dimer, factor assays, thrombophilia investigations and anticoagulant therapy monitoring
Ready-to-use liquid reagents and automated testing solutions designed for use with Sysmex haemostasis analysers
Clotting, chromogenic, immunological and specialised assay technologies – including high-sensitivity chemiluminescence enzyme immunoassay (CLEIA) on the HISCL platform – support efficient workflows and consistent performance
Integrated portfolio including Sysmex innovations such as Revohem, expanding capability and flexibility across routine and specialised testing

What's new

HISCL HIT IgG Assay Kit

Fast, reliable HIT IgG testing

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Revohem FIB LRT

Fast, ready to use

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Revohem Anti-Xa LRT

Precision anti-Xa testing

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Sysmex haemostasis reagent portfolio

Global assays

Factor assays

Anticoagulant monitoring

Thrombophilia

von Willebrand disease

D-Dimer

Fibrinolysis

Platelet aggregation

General purpose calibrator and controls

Auxiliary reagents

CLEIA

Global Assays

Prothrombin Time

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Innovin		✔	B4212-40 B4212-50 B4212-100	10873825 10873826 10873824	10 × for 4 mL 10 × for 10 mL 12 × for 20 mL	CN-6500/3500
Thromborel S			OUHP29 OUHP49	10873886 10873887	10 × for 4 mL 10 × for 10 mL
PT‑Multi Calibrator			OPAT03	10873847	6 level × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Activate Partial Thromboplastin Time

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Actin Activated Cephaloplastin	✔	✔	B4218-1 B4218-2	10873827 10873829	10 × 2 mL 10 × 10 mL
Actin FS Activated PTT	✔	✔	B4218-20 B4218-100	10873830 10873828	10 × 2 mL 10 × 10 mL
Actin FSL Activated PTT	✔	✔	B4219-1 B4219-2	10873831 10873832	10 × 2 mL 10 × 10 mL
Pathromtin SL	✔		OQGS29 OQGS35 10873816²	10873862 10873863 10873816²	10 × 5 mL 20 × 5 mL 10 × 10 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

² Specific country only.

Fibrinogen

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Revohem FIB LRT	✔	✔	AE024611	AE024611	6 × 5 mL
Thrombin reagent		✔	B4233-25 B4233-27	10873837 10873838	10 × for 1 mL 10 × for 5 mL
Fibrinogen Determination Reagents		✔	B4233-15SY	10873835	Kit
Data‑Fi Abnormal Fibrinogen Control Plasma			B4233-22	10873836	10 × for 1 mL
Multifibren U			OWZG19 OWZG23	10873900 10873901	10 × for 2 mL 10 × for 5 mL
Kaolin Suspension	✔	✔	OQAB45	10873859	1 × 50 mL
Fibrinogen Calibrator kit			OQVK11	10873868	6 level × 1 × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Thrombin Time/Batroxobin Time

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Thromboclotin		✔	281007	10873820	10 × for 10 mL
Test Thrombin		✔	OWHM13	10873894	10 × for 5 mL
Batroxobin Reagent			OUOV21	10873889	2 × for 5 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Factor Assays

Deficient Plasma

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Coagulation Factor II Deficient Plasma			OSGR13	10873878	3 × for 1 mL
Coagulation Factor V Deficient Plasma			ORSM19	10873875	8 × for 1 mL
Coagulation Factor VII Deficient Plasma			OTXV13	10873879	3 × for 1 mL
Coagulation Factor VIII Deficient Plasma			OTXW17	10873880	8 × for 1 mL
Coagulation Factor IX Deficient Plasma			OTXX17	10873881	8 × for 1 mL
Coagulation Factor X Deficient Plasma			OTXY13	10873882	3 × for 1 mL
Coagulation Factor XI Deficient Plasma			OSDF13	10873883	3 × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Chromogenic Assays

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Factor VIII Chromogenic Assay			B4238-40	10873840	Kit
Berichrom F XIII			OWSU11	10873897	Kit

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Anticoagulant monitoring

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Revohem Anti‑Xa LRT	✔	✔	CG217097 AL064127 BU634799	CG217097 AL064127 BU634799	3 x 3 mL 4 x 5 mL 4 x 7.5 mL
Revohem Anti‑Xa Diluent	✔	✔	AF018369 CW518576	AF018369 CW518576	4 x 20 mL 10 x 20 mL
Revohem Heparin Hybrid Calibrator			BQ221064	BQ221064	5 levels x 4 x 1 mL
Revohem UFH Control Plasma			AZ296682	AZ296682	2 levels x 6 x 1 mL
Revohem LMWH Control Plasma			CE227688	CE227688	2 levels x 6 x 1 mL
Revohem Apixaban Control			AY519357	AY519357	2 levels x 6 x 1 mL
Revohem Apixaban Calibrator			AP675507	AP675507	3 levels x 3 x 1 mL
Revohem Edoxaban Control			AD713277	AD713277	2 levels x 6 x 1 mL
Revohem Edoxaban Calibrator			CE077977	CE077977	3 levels x 3 x 1 mL
Revohem Rivaroxaban Control			BB808578	BB808578	2 levels x 6 x 1 mL
Revohem Rivaroxaban Calibrator			AC222492	AC222492	3 levels x 3 x 1 mL
Revohem Fondaparinux Control			BT830756	BT830756	2 levels x 6 x 1 mL
Revohem Fondaparinux Calibrator			CW731055	CW731055	4 levels x 3 x 1 mL
Revohem Danaparoid Control			CJ744965	CJ744965	2 levels x 6 x 1 mL
Revohem Danaparoid Calibrator			CE707939	CE707939	5 levels x 4 x 1 mL
INNOVANCE Heparin	✔	✔	OPOA03	10873916	Kit
INNOVANCE Anti‑Xa	✔	✔	OPPU05	10873942	Kit
INNOVANCE DTI Assay		✔	OPOH03	10873922	Kit
INNOVANCE Heparin Calibrator			OPOB03	10873867	5 levels x 1 x 1 mL
INNOVANCE Heparin UF Control 1			OPOC03	10873920	5 x for 1 mL
INNOVANCE Heparin UF Control 2			OPOD03	10873919	5 x for 1 mL
INNOVANCE Heparin LMW Control 1			OPOE03	10873917	5 x for 1 mL
INNOVANCE Heparin LMW Control 2			OPOF03	10873918	5 x for 1 mL
Dabigatran Controls			OPOK03	10873923	2 levels x 5 x for 1 mL
Dabigatran Standards			OPOL03	10873924	2 levels x 3 x for 1 mL
INNOVANCE Rivaroxaban Controls			OPPS03	10873940	2 levels x 5 x for 1 mL
INNOVANCE Rivaroxaban Standards			OPPT03	10873941	2 levels x 2 x for 1 mL
INNOVANCE Apixaban Controls			OPPV03	10873938	2 levels x 5 x for 1 mL
INNOVANCE Apixaban Standards			OPPW03	10873939	2 levels x 2 x for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Thrombophilia

Antithrombin

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
INNOVANCE Antithrombin	✔	✔	OPFH03 OPFH11 OPFH05	10873856 10873911 10873857	Small Kit Medium Kit Large Kit
Berichrom Antithrombin III			OWWR17 OWWR15	10873899 10873898	Small Kit Large Kit

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Protein C

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Protein C Reagent			OQYG11	10873871	Kit
Berichrom Protein C		✔	OUVV15 OUVV17	10873892 10873893	Large Kit Small Kit

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Protein S

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Protein S Ac			OPAP03	10873846	Kit
INNOVANCE Free PS Ag	✔	✔	OPGL03	10873858	Kit

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Activated Protein C resistance / Factor V Leiden

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
ProC Global			OQLS13	10873866	Kit
ProC Ac R			OPBC03	10873848	Kit
ProC Control Plasma			OQKE17	10873864	6 x 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Lupus anticoagulant

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
LA 1 Screening Reagent³		✔	OQGP17	OQGP17 (10446063)	10 × for 2 mL
LA 2 Confirmation Reagent³		✔	OQGR13	OQGR13 (10446064)	10 × for 2 mL
LA Control High³			OQWD11	OQWD11 (10446153)	6 × for 1 mL
LA Control Low³			OQWE11	OQWE11 (10446154)	6 × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

³ Available under Siemens brand.

von Willebrand disease

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
vWF Ag³	✔		OPAB03	OPAB03 10445967	Kit
INNOVANCE VWF Ac	✔	✔	OPHL03	10873906	Kit
BC von Willebrand Reagent			OUBD37	10873912	5 × for 4 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

³ Available under Siemens brand.

D-Dimer

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
D-Dimer Latex LRT*	✔	✔	120011	120011	5 x 4 mL Latex 5 x 7 mL Reaction buffer
INNOVANCE D‑Dimer			OPBP03 OPBP07	10873850 10873851	Small Kit Large Kit
INNOVANCE D‑Dimer Sample Diluent	✔	✔	OPBR03	10873905	10 × 5 mL
INNOVANCE D‑Dimer Controls			OPDY03	10873854	2 Level × 5 × 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

*Availability depends on country, please contact your local Sysmex representative.

Fibrinolysis

Coagulation/Fibrinolytic function

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Berichrom α2‑Antiplasmin			OUBU15	10873884	Kit
Berichrom Plasminogen		✔	OUCA17	10873885	Kit
Berichrom C1‑Inhibitor			OUIA15	10873888	Kit

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Platelet aggregation

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Revohem ADP			AP200422	AP200422	3 × for 0.625 mL
Revohem Collagen			AW993826	AW993826	3 × for 0.625 mL
Revohem Epinephrine			BJ882610	BJ882610	3 × for 0.625 mL
Revohem Arachidonic Acid			BV413997	BV413997	3 × for 0.625 mL
Revohem Ristocetin			BC444030	BC444030	3 × for 0.625 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Сhemiluminescent enzyme immunoassay (CLEIA)

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
HISCL HIT IgG Assay Kit*	✔		BB296616		Kit content: HISCL HIT IgG R1 reagent (3 mL x 1 ) HISCL HIT IgG R2 reagent (1.5 mL x 1 ) HISCL HIT IgG R3 reagent (5 mL x 1 )
HISCL HIT IgG Calibrator	✔		AR941147		Kit content: HISCL HIT IgG C0 (1 mL x 1 ) HISCL HIT IgG C1 (1 mL x 1 ) HISCL HIT IgG C2 (1 mL x 1 ) HISCL HIT IgG C3 (1 mL x 1 ) HISCL HIT IgG C4 (1 mL x 1 )
HISCL HIT IgG Control	✔		CL306546		Kit content: HISCL HIT IgG Control Level 1 (2 mL x 3 ) HISCL HIT IgG Control Level 2 (2 mL x 3 )
HISCL Diluent 4	✔		AY334828		20 mL × 1

*Availability depends on country, please contact your local Sysmex representative.

General purpose calibrator and controls

Calibrator

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Standard Human Plasma			ORKL17	10873908	10 × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Controls

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Standard Human Plasma			ORKL17	10873908	10 × for 1 mL
Control Plasma P			OUPZ17	10873890	10 × for 1 mL
Ci‑Trol 1 Ci‑Trol 2 Ci‑Trol 3			291070 291071 291072	10873821 10873822 10873823	10 × for 1 mL 10 × for 1 mL 10 × for 1 mL
Ci‑Trol Coagulation Control Level 1, 2 and 3			B4244-10 B4244-20 B4244-30	10873842 10873843 10873844	20 × for 1 mL 20 × for 1 mL 20 × for 1 mL
Ci‑Trol Heparin Control Low			B4224-50	10873833	10 × for 1 mL
Ci‑Trol Heparin Control High			B4224-60	10873834	10 × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Auxiliary reagents

Product	LIQ	NSTR	REF code	Material number	Packaging	Compatible instrument
Owren’s Veronal Buffer	✔	✔	B4234-25	10873839	10 × 15 mL
CA System Buffer	✔	✔	B4265-37	10873915	8 × 250 mL
Calcium Chloride Solution	✔	✔	ORHO37	10873872	10 × 15 mL
CN Coagwasher	✔	✔	AZ700649	AZ700649	2 L
CA Clean I	✔	✔	96406313	96406313	50 mL
CA Clean II	✔	✔	BT565104 96406136 97405810	BT565104 96406136 97405810	45 mL 500 mL 5 L
Hepzyme			B4240-10	10873841	10 × for 1 mL

LIQ: Liquid formulation, no reconstitution required.
NSTR: No Standing Time Required

Haemostasis reagent catalogue

Whether you require routine assays for bleeding risk management or specialised tests for thrombophilia and anticoagulant therapy management, our extensive portfolio caters to your diverse needs. This catalogue serves as your guide to a world-class selection of Sysmex haemostasis reagents.

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Regulatory Documents

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