Nucleated cell differential with comprehensive pre-classification into 17 cell types
Automatic location of suitable areas for the differential
Manual selection of differential areas when desired
Remote review by several experts, with preliminary signatures and extensive commenting functions
Reporting of results to the LIS, or create pdf reports including selected cell images
Traceability in area selection, re-classification, commenting and results

A new standard for bone marrow morphology – built on proven digital cell morphology expertise

Developed by digital cell morphology pioneers CellaVision, the Bone Marrow Aspirate (BMA) Application runs on the established CellaVision^®DC-1 digital morphology analyser using a 100x objective for excellent image quality. Using advanced AI technology, the BMA Application automatically locates, captures, pre-classifies and stores cell images based on their morphology. The level of automation can be adapted to your individual workflow and preference with three different analysis modes. You decide how much manual control you want to retain over the process.

Together with the CellaVision^® BMA Review Software, the BMA Application enables morphology review, consultation, and verification of cell differentials from anywhere, at any time. The cell images are displayed, and the pre-classification results are then reviewed and verified by one or more qualified bone marrow morphology experts as needed.

More details

AI-powered digital insight for consistent, efficient, and collaborative bone marrow analysis

CellaVision^® BMA Application simplifies and supports morphological examination of bone marrow aspirate samples in several innovative ways, promoting accuracy, reducing turnaround times, and elevating your bone marrow morphology expertise.

Key features:

Analyse multiple slides per order and select which slides to include in the results
Pre-classified cells are easily dragged and dropped into the appropriate cell class, if re-classification is needed
View cell images at adjustable magnification, in their surrounding and with cell classes side-by-side
Select, compare and review the slide regions used for analysis, view results per slide or particle-by-particle
Tag cells as dysplastic, and calculate % of dysplastic cells per lineage
Compare cells with previous results, another cell class, or reference cell images side-by-side, using split view
Generate overview images of smears for overall review or further analysis
Archive cell images as part of the patient’s medical history

Software packages

CellaVision^®BMA Review Software

Bone marrow morphology analysis benefits from shared expertise. With the CellaVision^® BMA Review Software, multiple experts can review, comment, and verify within the same case – supporting second opinions, training, and consistent decision-making across any distance and lab network.

Remote review and verification within the network
Commenting and collaboration tools for case discussion
Traceability of area selection and re-classification decisions
Flexible expert involvement when needed

CellaVision^® BMA Server Software

For laboratories with more than one analyser sharing the same database. The Server Software manages the database and connections to the analysers and review stations.

200 GB data storage solution
Connection of multiple analysers and concurrent users
Centralisation of workflows

Technical specifications

Analyser model	CellaVision^® DC-1, equipped with the BMA Application
Regulatory compliance	Class C under IVD-R
Technology	advanced artificial intelligence
Objective	100x
Slide preparation methods	wedge smear or squash preparation, with or without coverslip manual or automated staining (RAL StainBox)
Compatible stains	Romanowsky stains: May Grünwald Giemsa, Wright Giemsa, Wright RAL MCDh (methanol-free Kit RAL StainBox BBM)
Loading capacity	1 slide at a time
Throughput	3–4 slides/h, with 17 min/slide
Differential pre-classification	17 cell types including: Proerythroblast, Basophilic erythroblast, Polychromatic erythroblast, Orthochromatic erythroblast, Blast, Promyelocyte, Myelocyte, Metamyelocyte, Band neutrophil, Segmented neutrophil, Eosinophil, Basophil, Monocyte, Mast cell, Lymphocyte, Plasma cell, Other cells and artifacts (pre-classified into Macrophage, Smudge cell, Artifact) Users can add additional cell classes for manual re-classification.
Dysplastic cells	quantitative results presented as the percentage of cells in lineage tagged by the user as dysplastic, in the erythroid and myeloid lineages
M:E ratio	quantitative results presented as the M:E ratio based on user-classified cells in the myeloid and erythroid lineage
Reporting	Results can be saved in a pdf report and/or sent to the LIS
Storage capacity	30 MB – for approx. 650 analyses performed in automatic mode DC-1 database with customisable archiving function
Software options	BMA Server: 200 GB central storage, connection of multiple analysers to one database BMA Review: access to stored images for authorised users from anywhere at any time