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Nexus IB10 Analyzer
Nexus IB10 Analyzer: near-patient immunochromatography testing system
- Portable instrument with built-in printer
- Quantitative results from whole blood or plasma
- User-friendly and fully automated
- Time to result: up to 22 minutes
- Determines multiple analytes in a single run
- Results can be stored, viewed, printed, or transmitted to the LIS
Point-of-care testing system Nexus IB10 Analyzer
The Nexus IB10 Analyzer is a point-of-care (POC) solution for near-patient testing to provide accurate diagnostics of critically ill patients in acute and critical care settings. This analyser is a valuable addition to intensive care units (ICU), emergency departments (ED), and other near-patient testing settings, enabling clinicians to perform a wide range of commonly used whole blood or plasma tests, together with innovative biomarkers for the diagnosis, prognosis, and monitoring of acute and critical medical conditions.
Rapid point-of-care testing technology
POC testing significantly reduces the time that passes between performing clinical tests and the readiness of their results. The Nexus IB10 Analyzer is a compact, easy-to-use and fully automated POC system, utilising an immunochromatographic assay (ICA) method to measure and analyse results with a built-in sensor. Using whole blood or plasma samples, the test results are ready in up to 22 minutes and can be printed or sent directly to the laboratory information system (LIS). By simplifying the testing process, clinicians can focus on what matters most: Effective, quality patient care.
POC diagnostics made easy
The sphingotest® disc combines chemistry with centrifugal microfluidic flow to rapidly prepare cell-free plasma from whole blood, which can then flow through a channel to rehydrate, solubilise and mix with freeze-dried immunoconjugates. Using a combination of active flow and capillary action, the test is ready to be quantitatively measured within 22 minutes with an optical signal level proportional to the analyte concentration.
After adding the patient sample, the entire test is performed within the Nexus IB10 Analyzer, which controls everything from the temperature of the disc, the sequence, duration of measurement, centrifugal flow, mixing, incubation time, final signal measurement and quantitation right up to the reporting of results. The disc also includes a positive internal control to ensure that the test device has operated properly.
Each lot of discs is calibrated for the specific analytes to be measured to ensure that the lot-to-lot variability is minimised. Lot-specific calibration along with additional information such as the lot expiration date is contained on the QR code label affixed to each disc. It is recommended that quality controls also be run at appropriate time intervals to confirm that the reagent lot is performing within acceptable limits.
IB10 sphingotest® product portfolio
Innovative acute and critical care biomarkers
SphingoTec develops and markets innovative in vitro diagnostic (IVD) tests for innovative biomarkers for the diagnosis, prognosis, and monitoring of acute medical conditions, such as septic shock and circulatory failure, acute heart failure, and acute kidney injury in order to support patient management and provide guidance for treatment strategies.
|Item number||Test name||Parameters||Sample material|
|IVR-IB62||IB10 sphingotest® penKid®||proenkephalin A 119-159||EDTA whole blood / plasma|
|IVR-IB61||IB10 sphingotest® bio-ADM®||bioactive adrenomedullin 1-52||EDTA whole blood / plasma|
|IVR-IB58||IB10 sphingotest® DPP3||dipeptidyl peptidase 3||EDTA whole blood / plasma|
|Item number||Test name||Parameters||Sample material|
|IVR-IB65 *||IB10 sphingotest® PCT||procalcitonin||EDTA whole blood / plasma|
|IVR-IB56 *||IB10 sphingotest® NT-proBNP||NT-proBNP||Li-heparin or EDTA whole blood / plasma|
|IVR-IB52 *||IB10 sphingotest® D-Dimer||D-dimer||Li-heparin or citrated whole blood / plasma|
|IVR-IB50 *||IB10 sphingotest® Troponin-99||troponinI||Li-heparin whole blood / plasma|
|IVR-IB55 *||IB10 sphingotest® TSH||TSH||Li-heparin whole blood / plasma|
|IVR-IB54 *||IB10 sphingotest® beta-hCG||beta-hCG||Li-heparin whole blood / plasma|
|IVR-IB53 *||IB10 sphingotest® Shortness of Breath||D-dimer, NT-proBNP, troponin I||Li-heparin whole blood / plasma|
|IVR-IB51||IB10 sphingotest® 3-in-1 Cardiac||troponin I, CK-MB, myoglobin||Li-heparin whole blood / plasma|
* For these parameters, quality control materials in two levels are available.
Key specifications 
|Model name||Nexus IB10 Analyzer|
|Sample type||whole blood and plasma|
|Sample volume||500 µL|
|Time to result||up to 22 min |
|Display||109 mm LCD touch screen|
|Quality control|| |
system performance: EQC – Electronic Qualification Control (IVR-IB60)
|Printer||built-in thermal printer|
|Connectivity||USB / PC, LIS, ASTM, HL7|
|Dimensions (W x H x D)||177 x 177 x 330 mm|
 For more details, please refer to the IFU.
 For all biomarkers, the time to result is 20 minutes, except for IB10 sphingotest® DPP3, for which the time to result is 22 minutes.
Sysmex Europe SE
+49 (40) 527 26 0
+49 (40) 527 26 100
Regulatory documents, such as Instructions for Use, can be accessed with a valid My Sysmex login:Go to My Sysmex