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Sysmex UF-500


  • Detects potential urinary tract infections within a minute, not hours
  • Detects all three UTI indicators in one go, at a rate of up to 60 samples/h
  • Distinguishes between inflammation, bacterial and mycotic infections
  • Unattended walk-away for improved productivity
  • Easy to operate via interactive menus


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UF-500i – High-quality urinalysis at the touch of a button

Our new UF-series of urinalysis devices is unique. Using fluorescence flow cytometry, the UF-500i offers two separate channels: one for bacteria and one for sediment particles. This means you can now detect possible urinary tract infections in about one minute instead of hours at a rate of up to 60 samples per hour. And with its other diagnostic indicators, you can easily indicate contaminations, inflammations, bacterial and mycotic infections.

You can improve your productivity levels thanks to negative sample avoidance, unattended walkaway operation and full automation. Of course, it’s all backed by Sysmex’s globally renowned service and support.

Sysmex is known around the world for its world-leading haematology analysers based on fluorescence flow cytometry. We have now successfully applied this best-in-class technology to urinalysis and body fluid analyses that need high quality results, even in clinically relevant low concentration ranges.

Our analysers offer greater clinical value and enhanced productivity. This translates into faster, more sensitive analysis for patients, and an improved cost-result ratio for users.


Comprehensive, efficient urinalysis

Comprehensive, efficient urinalysis

The UF-500i has two separate analysis channels: one for bacteria, and one for all other particles. This lets you optimise your analysis with specifically adapted reagents in each channel (fluorescence marker and diluent). It also means you can selectively analyse either bacteria, or the complete profile of all particles. For a full list of parameters, please click on specifications.   
The UF-500i detects bacteria, leucocytes and yeast-like cells, and therefore covers all three main indicators for urinary tract infections in one go. So you can easily distinguish between a contamination, inflammation, bacterial or mycotic infection. You also have clinically useful information on haematuria and urine concentration at your disposal thanks to RBC characterisation and urine conductivity.

Speed and efficiency

Speed and efficiency

We have focused specifically on enhancing productivity and making the device more efficient to use. Thanks to an unattended walkaway function that allows continuous feeding of samples, and auto-validation with no image review or classification, you can significantly enhance your productivity.

The UF-500i can analyse up to 60 samples per hour. And because turnaround time has been cut dramatically, you can have your results and communicate them in minutes, instead of the standard hours-long wait. That’s good for you, and good for patients. 

Fluorescence Flow Cytometry for greater accuracy and speed

Fluorescence Flow Cytometry for greater accuracy and speed

Unlike standard urinalysis devices, the UF-500i offers two analysis technologies: fluorescence flow cytometry (FFC) with hydrodynamic focusing, and regular conductometry.

This offers significant benefits over standard analysers. The diode lasers used in our unique FFC method last significantly longer than standard gas lasers, are smaller, and use significantly less power.

The FFC combined with hydrodynamic focusing and refined lenses is capable of analytically classifying over 65,000 particles per sample. By specifically labelling nucleic acids contained in urinary particles with fluorescence markers, the UF-500i can automatically categorise particles based on several criteria (outer shape, inner complexity, surface structure, DNA content, etc.) instead of just size and appearance. This improves reproducibility and standardisation, an important attribute for accredited laboratories. And because hydrodynamic focusing means the device looks at a large analysis volume in the given time, it’s more sensitive.

Importantly, it can also analyse turbid samples.

Quality control and reagents

Quality control and reagents

The high quality of our devices and service always distinguishes us from the competition. Our focus on quality control is no different. The QC programme in the UF-500i offers ample storage space for QC data (5,000 samples and information on 5,000 patients).

Our UF II CONTROL material makes daily QC easy. You can enter lot information and target values via a barcode scanner – which saves time and prevents manual errors. It’s available in two concentrations for result values in the high and slightly pathologic range.

Intuitive and connected

Intuitive and connected

Apart from the actual start button, you can operate the UF-500i entirely automatically using the information-processing unit, or IPU. Thanks to intuitive menus and icons, it is extremely easy to use. And through the IPU database, you have direct access to patient data, test orders and all analysis results, including scattergrams, histograms and QC data.

The IPU makes data handling easier. It offers patient-related cumulative data as well as the famous Q-flags proven many times over in Sysmex haematology systems. There is a full error and user database and you can connect the UF-500i to our Extended IPU system and therefore link to remote labs and other databases. 

With multi-lingual operator software, an extended data storage capacity, network capabilities and flexible connectivity to peripheral devices such as Host, barcode scanner and printers, the UF-500i is ready for the future. 




fluorescence flow cytometry with diode laser and hydrodynamic focussing


2 separate channels: 1 for bacteria, 1 for all sediment particles



conductivity, RBC info, UTI info


normal mode: up to 60 samples/hour

special (high precision bacteria) mode: up to 45 samples/hour

Sample volumes

4 mL for sampler mode

1mL for manual mode

Data storage

5,000 samples (incl. graphics)

5,000 patients’ information

3,000 selective test orders

Quality control

24 QC files with 300 data points each

2-level control material UF II CONTROL in slightly and strongly

pathologic range


Windows® user interface

Host (Ethernet or serial)

graphic and/or line printer (USB)

bar code scanner (USB)


rack samplers for 50 (5 x 10 or 10 x 5) sample tubes

incl. bar code reader for sampler mode

hand-held bar code reader for manual mode

printer (graphic and /or line printers)


with work area management system sis-u

additional possibility of test strip reader connection to sis-u


w x h x d [mm] / [kg]

580 x 615 x 710 / 75.5 (main unit with sampler)

305 x 85 x 345 / 8 (IPU: information-processing unit)


Sysmex Europe GmbH

+49 (40) 527 26 0
+49 (40) 527 26 100
Bornbarch 1
22848 Norderstedt

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