Metastatic lymph node (LN) involvement is a major prognostic factor in gynaecological cancers and impacts the surgical approach as well as therapy choice. Nodal staging by systematic pelvic lymphadenectomy is associated with high risk of complications and post-surgical morbidity. Furthermore, its utility in early stage disease is challenged by the low frequency of nodal positivity and controversy about its curative effect. Sentinel lymph node biopsy (SLNB) is gaining increasing acceptance as an alternative to lymphadenectomy in the management of early stage cervical (CeC) and endometrial (EC) cancer patients, with the aim to avoid unnecessary lymphadenectomies and enable less radical surgical interventions to benefit the patient’s quality of life.
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19-08-20
