Axillary lymph node (ALN) status is still one of the most important prognostic factors for patients with breast cancer. As a result, an accurate and standardised determination of metastatic nodal burden within the ALN is of utmost importance when selecting the correct treatment, thus avoiding over- as well as under-treatment. Molecular analysis of sentinel lymph nodes (SLN) by quantification of CK19 mRNA expression with OSNA has shown to provide more differentiated diagnostic information compared to conventional histopathology.
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