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In this case report laboratory results of a two-year-old patient presented at the hospital with watery stool (later bloody stool with fever appearing) are shown. The CBC measured on XR-Series showed leucocytosis, anaemia, thrombocytopenia and schistocytes. Further test results revealed acute kidney injury, elevated lactate dehydrogenase (LD), an increase in C-reactive protein (CRP) and antibodies to Escherichia coli O157 lipopolysaccharide were found as well. This led to the suspicion of haemolytic uraemic syndrome due to Shiga toxin-producing E. coli.
What you always wanted to know about haemophilia can be found in this SEED. Starting with what haemophilia actually is, this article outlines the cause, effects and late effects, as well as former and current treatment methods. The reader will also receive guidance on the laboratory diagnosis of haemophilia A and B, as well as on the detection of anti-factor VIII antibodies.
Urinary tract infections (UTI) belong to the most common bacterial infections and, though suspected cases often turn out to be negative, contribute to high laboratory workloads and empiric prescription of antibiotics, a main driver antimicrobial resistance (AMR). This white paper reviews the strengths of the UF-series in ruling-out UTI, supporting its diagnosis and potential applications to further optimise the UTI laboratory workflow, aiming to fight AMR.
Diagnostics play a major role in the rational prescription of antibiotics. Well-known antimicrobial susceptibility tests (AST) are reliable tools for the phenotypic determination of resistance to antibiotics . Several solutions to support AST performance are available on the market.
This case study explains how the same lymphocytes react in two different complementary methods: fluorescence flow cytometry in the WPC channel of the XN-Series haematology analyser and multicolour immunophenotyping using the XF-1600 analyser. The haematology analyser detected a lymphocytosis and a suspect flag for ‘Abnormal Lympho?’. Subsequently, clinical flow cytometry was performed and the markers confirmed the diagnosis of a B-CLL in this patient.
This clinical information card focuses on the clinical use of IPF# (immature platelet fraction abolsute count) for coronary artery disease patients. The parameter helps monitoring the efficacy of antiplatelet drug therapy and assessing the risk of future cardiovascular thrombotic events.