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Follicular lymphoma (FL) is the most common form of indolent lymphoma in the western world, accounting for approximately 25% of malignant lymphomas (Ciabanu et al 2013). Disease progression of FL is often unpredictable with 25% - 30% of FL cases progressing; most commonly to diffuse large B cell lymphoma, Hodgkin lymphoma, Burkitt lymphoma and rarely B-lymphoblastic leukaemia/lymphoma (B-ALL) (Swerdlowetal, 2017).
We aim to offer a complete diagnostic solution to support clinicians in haematologic cancer management, provide complete information during each phase of the disease, allow a personalised approach and contribute to the improvement of patient outcomes. Next to our well-known haematology and smear workflow portfolio during recent years, technologies like antibody-based flow cytometry or FISH have been incorporated into our developmental capabilities. In this brochure Sysmex’s comprehensive solutions from screening to diagnosis and from treatment to monitoring in haemato-oncology are described, including haematology, clinical flow cytometry and molecular genetics.
This clinical case reports the disease progression of a patient hospitalised due to a SARS-CoV-2 infection. The patient’s condition worsens significantly over time, ultimately leading to the development of an acute respiratory distress syndrome (ARDS), a common but very severe complication in respiratory tract infections (such as COVID-19).
Cerebrospinal fluid as sample material requires particular attention at all times, from sample collection and transport to laboratory diagnostics. Upon arrival at the laboratory, the CSF sample must be processed quickly with great care and expertise so that the analysis results provide the information needed by the physician for treatment decisions. In this article you find a summary of all lab procedures with a focus on cell count and differentiation.
This case report deals with leptomeningeal carcinomatosis, a rare and severe complication of cancer in which the disease spreads into the membranes (meninges) surrounding the brain and spinal cord. In addition to that, it outlines how the HF-BF research parameter can be supportive.
The early differentiation of the underlying cause of canine anaemia is one of the biggest diagnostic challenges for veterinary clinicians. The reticulocyte count, together with the study of the different circulating degrees of maturity may allow a much more thorough and detailed assessment of each patient in the veterinary lab. In this preliminary study, reference ranges have been established for reticulocyte maturity fractions. Following the assessment of more than 150 anaemic patients, the Ecija-Mendoza diagram was created, a diagnostic tool that allows the differentiation between conditions caused by haemolysis, acute haemorrhage and anaemia due to dyserythropoiesis to allow the clinician to quickly form a suspected diagnosis.